Sketchy Pharmacology — Course Playlist

1

Autonomic Drugs: Parasympathetic

3 lessons

• 1.1 - Cholinomimetics TRIAL
• 1.2 - Acetylcholinesterase inhibitors
• 1.3 - Muscarinic antagonists TRIAL

2

Autonomic Drugs: Sympathetic

4 lessons

• 2.1 - Sympathomimetics
• 2.2 - Indirect sympathomimetics
• 2.3 - Alpha drugs
• 2.4 - Beta blockers

3

Cardiovascular and Renal: Heart Failure Drugs

3 lessons

• 1.1 - Digoxin
• 1.2 - ACE inhibitors_ ARBs_ Aliskiren
• 1.3 - Sacubitril-Valsartan_ Milrinone_ Nesiritide_ Ivabradine

4

Cardiovascular and Renal: Diuretics

4 lessons

• 2.1 - Acetazolamide_ mannitol
• 2.2 - Loop diuretics
• 2.3 - Thiazides
• 2.4 - K+ sparing diuretics

5

Cardiovascular and Renal: Antihypertensives

2 lessons

• 3.1 - Calcium channel blockers
• 3.2 - Primary hypertension and hypertensive emergency

6

Cardiovascular and Renal: Antiarrhythmics

5 lessons

• 4.1 - Class I A-C
• 4.2 - Class II
• 4.3 - Class III
• 4.4 - Class IV
• 4.5 - Class V

7

Blood and Inflammation: Anticoagulants and Thrombolytics

4 lessons

• 1.1 - Heparin_ LMWH_ fondaparinux_ direct thrombin inhibitors_ Xa inhibitors
• 1.2 - Warfarin
• 1.3 - Antiplatelet agents
• 1.4 - Thrombolytics

8

Blood and Inflammation: Dyslipidemia Drugs

4 lessons

• 2.1 - Statins
• 2.2 - Cholestyramine_ ezetimibe
• 2.3 - Fibrates_ niacin
• 2.4 - PCSK9 inhibitors

9

Blood and Inflammation: Anti-Inflammatory

2 lessons

• 3.1 - NSAIDs
• 3.2 - Gout drugs

10

Smooth Muscle: Vasoactive

3 lessons

• 1.1 - Nitrates
• 1.2 - Triptans and migraine
• 1.3 - Prostaglandins_ prostacyclin_ bosentan_ PDE5 inhibitors

11

Smooth Muscle: Allergy and Pulmonary

2 lessons

• 2.1 - Antihistamines
• 2.2 - Asthma therapy

12

GI and Endocrine: GI

6 lessons

• 1.1 - Antiemetic agents
• 1.2 - Antiemetic agents [Old Version]
• 1.3 - H2 receptor blockers_ PPIs
• 1.4 - Laxatives
• 1.5 - Antidiarrheals
• 1.6 - Laxatives and antidiarrheal agents - Old Version

13

GI and Endocrine: Diabetes

2 lessons

• 2.1 - Insulin_ sulfonylureas_ meglitinides_ GLP-1 agonists_ DPP-4 inhibitors
• 2.2 - Metformin_ thiazolidinediones_ pramlintide_ SGLT2 inhibitors

14

GI and Endocrine: Thyroid_ Parathyroid and Adrenal

4 lessons

• 3.1 - Propylthiouracil_ methimazole_ levothyroxine
• 3.2 - Bisphosphonates_ raloxifene_ denosumab_ calcitonin
• 3.3 - Teriparatide_ vitamin D_ cinacalcet_ sevelamer
• 3.4 - Glucocorticoids

15

GI and Endocrine: Hypothalamic and Pituitary

2 lessons

• 4.1 - Growth hormone_ mecasermin_ octreotide_ pegvisomant
• 4.2 - ADH_ DDAVP_ ADH receptor antagonists

16

GI and Endocrine: Sex Hormones

1 lesson

• 5.1 - SERMs and Aromatase Inhibitors

17

Neuro-Psych: Anesthetics and Analgesics

3 lessons

• 1.1 - Propofol_ etomidate_ ketamine
• 1.2 - Inhaled anesthetics_ dantrolene
• 1.3 - Opiates_ naloxone_ naltrexone

18

Neuro-Psych: Antidepressants and Anxiolytics

4 lessons

• 2.1 - SSRIs_ SNRIs_ cyproheptadine
• 2.2 - Tricyclic antidepressants
• 2.3 - MAO inhibitors
• 2.4 - Bupropion_ mirtazapine_ trazodone

19

Neuro-Psych: Mood Stabilizers and Antiepileptic Drugs

6 lessons

• 3.1 - Lithium
• 3.2 - Valproate_ topiramate_ lamotrigine_ levetiracetam_ brivaracetam
• 3.3 - Valproate_ topiramate_ lamotrigine_ levetiracetam - Old Version
• 3.4 - Ethosuximide
• 3.5 - Carbamazepine_ oxcarbazepine_ phenytoin_ tiagabine_ vigabatrin
• 3.6 - Gabapentin_ tiagabine_ vigabatrin

20

Neuro-Psych: Antipsychotics and Parkinson-s

3 lessons

• 4.1 - First generation antipsychotics
• 4.2 - Second generation antipsychotics
• 4.3 - Levodopa-carbidopa_ entacapone_ tolcapone_ selegiline_ ropinirole_ pramipexole_ amantadine

21

Neuro-Psych: Psychostimulants and Narcolepsy

1 lesson

• 5.1 - Armodafinil and Modafinil

22

Neuro-Psych: Sedative-Hypnotics

3 lessons

• 6.1 - Benzodiazepines_ flumazenil
• 6.2 - Nonbenzodiazepine hypnotics_ melatonin_ ramelteon
• 6.3 - Barbiturates

23

Antimicrobials: Cell Wall and Membrane Active Antibiotics

8 lessons

• 1.1 - Penicillin
• 1.2 - Nafcillin_ Oxacillin_ Methicillin and Dicloxacillin
• 1.3 - Ampicillin_ Amoxicillin_ Piperacillin_ Ticarcillin
• 1.4 - Cephalosporins
• 1.5 - Monobactams and Carbapenems
• 1.6 - Vancomycin
• 1.7 - Daptomycin
• 1.8 - Daptomycin - Old Version

24

Antimicrobials: Inhibitors of Bacterial Protein Synthesis

7 lessons

• 2.1 - Tetracyclines
• 2.2 - Macrolides
• 2.3 - Macrolides - Old Version
• 2.4 - Clindamycin
• 2.5 - Chloramphenicol
• 2.6 - Linezolid
• 2.7 - Aminoglycosides

25

Antimicrobials: Antimycobacterials

2 lessons

• 3.1 - Tuberculosis Drugs
• 3.2 - Leprosy drugs

26

Antimicrobials: Other Antibiotics

3 lessons

• 4.1 - Trimethoprim-Sulfamethoxazole
• 4.2 - Fluoroquinolones
• 4.3 - Metronidazole

27

Antimicrobials: Antifungals

3 lessons

• 5.1 - Amphotericin_ flucytosine
• 5.2 - Azoles
• 5.3 - Griseofulvin_ Terbinafine_ Echinocandins

28

Antimicrobials: Antivirals HIV

4 lessons

• 6.1 - NRTIs
• 6.2 - NNRTIs
• 6.3 - Protease inhibitors
• 6.4 - Maraviroc_ fusion inhibitors_ integrase inhibitors

29

Antimicrobials: Antivirals Other

3 lessons

• 7.1 - Acyclovir_ valacyclovir_ famciclovir
• 7.2 - Hepatitis C Direct-acting antivirals - DAAs
• 7.3 - Ganciclovir_ valganciclovir_ foscarnet_ cidofovir

30

Antineoplastics: Antimetabolites

3 lessons

• 1.1 - Methotrexate_ leucovorin_ 5-fluorouracil_ hydroxyurea
• 1.2 - Azathioprine_ 6-mercaptopurine_ mycophenolate mofetil
• 1.3 - Cladribine_ cytarabine_ gemcitabine

31

Antineoplastics: DNA and Cellular Division

5 lessons

• 2.1 - Cyclophosphamide_ ifosfamide_ busulifan_ nitrosoureas - carmustine_ lomustine_ streptozocin
• 2.2 - Cisplatin_ carboplatin_ oxaliplatin_ amifostine
• 2.3 - Bleomycin_ doxorubicin_ daunorubicin_ actinomycin D
• 2.4 - Etoposide_ teniposide_ topotecan_ irinotecan
• 2.5 - Vincristine_ vinblastine_ paclitaxel

32

Antineoplastics: Kinase Inhibitors and Monoclonal Antibodies

2 lessons

• 3.1 - Imatinib_ erlotinib_ sorafenib_ sunitinib_ vemurafenib
• 3.2 - Rituximab_ cetuximab_ bevacizumab_ alemtuzumab_ trastuzumab

33

Antineoplastics: Immunology

1 lesson

• 4.1 - Interferon a_ b_ y

34

Pharmacology Foundations: Pharmacokinetic Basics

2 lessons

• Membranes- Partition Coefficient_ Passive Diffusion and Active Transport
• Plasma Concentration and Therapeutic Range

35

Pharmacology Foundations: Absorption

2 lessons

• Oral Drug Absorption and Bioavailability - F
• Introduction to Drug Absorption via Parenteral Routes

36

Pharmacology Foundations: Distribution

2 lessons

• Drug Distribution and Protein Binding
• Volume of Distribution

37

Pharmacology Foundations: Metabolism

2 lessons

• Introduction to CYP450 Enzymes
• P-Glycoprotein and Enterohepatic Recycling

38

Pharmacology Foundations: Elimination

2 lessons

• Clearance and Area Under the Curve
• Elimination-Rate Constant_ Half-Life and Steady State

39

Pharmacology Foundations: Pharmacodynamic Basics

1 lesson

• Agonists_ Antagonists and Allosteric Modulators

40

Pharmacology Foundations: Drug-Drug Interactions

1 lesson

• Introduction to Pharmacodynamic and Pharmacokinetic Drug Interactions